I love medium format, but medium format cameras and travel are not generally a good combination.  The cameras and lenses are large and heavy.  About a year ago, I determined that I was giving up on taking my Mamiya 645 Pro TL on long trips.  The system is modular and breaks down nicely,  but each lens adds about a pound of weight.  I took it with me to San Francisco, limiting myself only to the 80mm lens, but for trips to the Caribbean where small planes and weight limitations are common, it has to be left behind.  The good thing is that I have a compact alternative for shooting medium format…